Mechanism of Botulinum Toxin Model
Product Code : JC-BE-6201
The Mechanism of Botulinum Toxin Model (SKU JC-BE-6201) is a botulinum toxin model that shows how the toxin of Clostridium botulinum acts at the presynaptic terminal of the neuromuscular junction. It shows the toxin cleaving SNARE proteins so that vesicles cannot release acetylcholine, the resulting block of nerve-to-muscle signalling and the descending flaccid paralysis of botulism. It is used in microbiology, physiology and pharmacology teaching. JaincoLab manufactures it in Ambala, India.
Specifications
The model is a microbiology teaching model of botulinum toxin action, covering the toxin source, target site, SNARE protein cleavage, blocked acetylcholine release and clinical outcome; its dimensions, material and base are not in the current product data and are confirmed on the quotation.
| Product | Mechanism of Botulinum Toxin Model |
| SKU | JC-BE-6201 |
| Model type | Microbiology teaching model |
| Subject depicted | Action of botulinum toxin at the neuromuscular junction |
| Topics shown | Toxin source (Clostridium botulinum), presynaptic terminal of the neuromuscular junction, cleavage of SNARE proteins, blocked acetylcholine release and descending flaccid paralysis |
| Size, material and base | Confirmed on the quotation |
Uses of the botulinum toxin model
Lecturers use the model to connect a molecular event, the cutting of SNARE proteins, with a whole-body effect, the flaccid paralysis seen in botulism.
- Locating the presynaptic terminal of the neuromuscular junction
- Explaining SNARE-dependent release of acetylcholine
- Showing how toxin cleavage of SNARE proteins blocks transmission
- Discussing descending flaccid paralysis in botulism
- Microbiology, physiology and pharmacology teaching
Scope of supply and ordering
Each unit is a single Mechanism of Botulinum Toxin Model depicting how botulinum toxin blocks the neuromuscular junction, supplied for classroom and laboratory teaching. Construction details not listed above, and any accessories, spares and quantities, are confirmed on the quotation.
Minimum order quantity, lead time and packing are confirmed on each quotation for the quantity and delivery destination. JaincoLab supplies single-institution orders as well as bulk requirements for schools, colleges and education projects.
Frequently asked questions
Where does the toxin act on the model?
At the presynaptic terminal of the neuromuscular junction, where it prevents acetylcholine release.
What molecular step is shown?
Cleavage of the SNARE proteins that vesicles need to release acetylcholine, which blocks signalling from nerve to muscle.
Related products
- Clostridium Species and Summary of Disease Model
- Bacillus Species Anthrax Model
- Staphylococcal Species and Disease Model
- Bacterial Families Model
For a full laboratory set, see the biology lab equipment range from JaincoLab, which covers models and other teaching aids.
Request a quote
To order the Mechanism of Botulinum Toxin Model, send the SKU JC-BE-6201, the quantity and the delivery destination through the JaincoLab contact page or email [email protected]. Tender and project enquiries can be sent through the tenders page.
